Table 1.
Patient Demographics and Clinicopathologic Characteristics
| Patient Characteristics | Right-Sided Primary (Total=329) | Left-Sided Primary (Total=578) | |
|---|---|---|---|
| N (%) | N (%) | p | |
| Age at Surgery, median (range) | 65.4 (26–86) | 62.6 (23–89) | <0.001 |
| Gender | 0.553 | ||
| Male | 180 (54.7) | 328 (56.7) | |
| Female | 149 (45.3) | 250 (43.3) | |
| T stage for primary tumor | 0.885 | ||
| 1 | 9 (2.7) | 13 (2.2) | |
| 2 | 38 (11.6) | 69 (11.9) | |
| 3 | 241 (73.3) | 412 (71.3) | |
| 4 | 25 (7.6) | 48 (8.3) | |
| Unknown | 16 (4.9) | 36 (6.2) | |
| N stage for primary tumor | 0.144 | ||
| N0 | 126 (38.3) | 223 (38.6) | |
| N1 | 113 (34.3) | 231 (40.0) | |
| N2 | 88 (26.7) | 119 (20.6) | |
| Unknown | 2 (0.6) | 5 (0.9) | |
| LVI for primary tumor | 0.665 | ||
| No | 108 (32.8) | 183 (31.7) | |
| Yes | 82 (24.9) | 160 (27.7) | |
| Unknown/Missing | 139 (42.2) | 235 (40.7) | |
| PNI for primary tumor | 0.318 | ||
| No | 122 (37.1) | 186 (32.1) | |
| Yes | 35 (10.6) | 69 (11.9) | |
| Unknown/Missing | 172 (52.3) | 323 (55.9) | |
| Tumor grade | 0.157 | ||
| Well | 4 (1.2) | 16 (2.8) | |
| Moderate | 255 (77.5) | 451 (78.0) | |
| Poor | 34 (10.3) | 41 7.1) | |
| Unknown/Missing | 36 (10.9) | 70 (12.1) | |
| CEA | 0.155 | ||
| <200 | 255 (77.5) | 447 (77.3) | |
| ≥200 | 38 (11.6) | 48 (8.3) | |
| Unknown/Missing | 36 (10.9) | 83 (14.3) | |
| DFI | 0.002 | ||
| <12 month | 202 (61.4) | 292 (50.5) | |
| ≥12 month | 127 (38.6) | 286 (49.5) | |
| Size of largest liver tumor | 0.858 | ||
| <5 | 222 (67.5) | 387 (67.0) | |
| ≥5 | 107 (32.5) | 191 (33.0) | |
| Multiple liver tumor | 0.809 | ||
| 1 | 172 (52.3) | 307 (53.1) | |
| >1 | 157 (47.7) | 271 (46.9) | |
| Clinical Risk Score | 0.664 | ||
| 0–2 | 172 (52.3) | 283 (49.0) | |
| 3–5 | 119 (36.2) | 209 (36.2) | |
| Unknown | 38 (11.6) | 86 (14.9) | |
| Extrahepatic Disease | 0.263 | ||
| No | 304 (92.4) | 545 (94.3) | |
| Yes | 25 (7.6) | 33 (5.7) | |
| Margin | 0.191 | ||
| Negative | 308 (93.6) | 527 (91.2) | |
| Positive | 21 (6.4) | 51 (8.8) | |
| Perioperative Chemotherapy | 0.919 | ||
| Yes | 304 (92.4) | 533 (92.2) | |
| No | 25 (7.6) | 45 (7.8) | |
| Hepatic Artery Infusion Pump | 0.381 | ||
| Yes | 103 (31.3) | 165 (28.5) | |
| No | 226 (68.7) | 413(71.4) |