Table 2.
Chosen treatments by clinical scenario.
| Treatment | Clinical Scenario* |
||||
|---|---|---|---|---|---|
| 1 (n = 839) | 2 (n = 842) | 3 (n = 841) | 4 (n = 840) | 5 (n = 838) | |
| Symptomatic treatment only,% | 71 | 10 | 5 | 1 | 1 |
| Chloroquine/Hydroxychloroquine,% | 25 | 81 | 85 | 84 | 78 |
| Lopinavir/Ritonavir,% | 3 | 22 | 33 | 46 | 40 |
| Azithromycin,% | 14 | 50 | 60 | 62 | 57 |
| Remdesivir,% | 1 | 8 | 8 | 23 | 32 |
| Interferon beta-1b/alfa-2,% | 0 | 1 | 2 | 5 | 8 |
| Low-dose corticosteroids,% | 1 | 8 | 7 | 22 | 16 |
| Pulse steroid therapy (>250 mg of methylprednisolone or equivalent),% | 1 | 4 | 4 | 26 | 57 |
| Empirical antibiotic therapy,% | 2 | 1 | 29 | 48 | 54 |
| Tocilizumab or another monoclonal antibody,% | 1 | 4 | 4 | 33 | 72 |
| Mean number of drugs (SD) | 0.6 (1.2) | 2.1 (1.3) | 2.4 (1.2) | 3.6 (1.4) | 4.3 (1.4) |
SCENARIO 1: Mildly symptomatic infection in an outpatient <65 years without comorbidity, without radiological involvement and with baseline oxygen saturation >95% on room air.
SCENARIO 2: Mildly symptomatic infection without pneumonia in a patient aged ≥65 years and/or comorbidity and/or oxygen saturation <95% on room air.
SCENARIO 3: Radiologically confirmed mild pneumonia, CURB-65 score pneumonia severity index ≤1 and oxygen saturation ≥95% on room air.
SCENARIO 4: Radiologically confirmed severe pneumonia who did not meet the ARDS criteria, CURB-65 score pneumonia severity index >1 and/or oxygen saturation <95% on room air.
SCENARIO 5: Severe pneumonia who met the ARDS criteria, CURB-65 score pneumonia severity index >1 and/or oxygen saturation <95% on room air.
Abbreviations: ARDS, acute respiratory distress syndrome; SD, standard deviation.