Table 2:
Illustration of Weighting and Replication for End-of-Study Outcome Comparison of Embedded Adaptive Interventions, Using Simulated Data
| Unmodified data layout | ||||||
|---|---|---|---|---|---|---|
| Individual ID | Response Status* | Month | Y | |||
| 1001 | 0 | 3 | 1 | −1 | 24 | |
| 1002 | 1 | 3 | −1 | NA | 26 | |
| 1003 | 0 | 3 | 1 | 1 | 28 | |
| 1004 | 0 | 3 | −1 | −1 | 30 | |
| 1005 | 1 | 3 | −1 | NA | 27 | |
| 1006 | 1 | 3 | 1 | NA | 28 | |
| Weighted and replicated data layout | ||||||
| Individual ID | Response Status | Month | Y | W | ||
| 1001 | 0 | 3 | 1 | −1 | 24 | 4 |
| 1002 | 1 | 3 | −1 | 1 | 26 | 2 |
| 1002 | 1 | 3 | −1 | −1 | 26 | 2 |
| 1003 | 0 | 3 | 1 | 1 | 28 | 4 |
| 1004 | 0 | 3 | −1 | −1 | 30 | 4 |
| 1005 | 1 | 3 | −1 | 1 | 27 | 2 |
| 1005 | 1 | 3 | −1 | −1 | 27 | 2 |
| 1006 | 1 | 3 | 1 | 1 | 28 | 2 |
| 1006 | 1 | 3 | 1 | −1 | 28 | 2 |
*
Response status is coded such that 0=non-responder; 1=responder