Figure 2.

Amino acid sequence comparisons of zebrafish Crb1 with human, mouse, and zebrafish Crb proteins. A, Pairwise comparisons of the sequence identities and similarities between zebrafish Crb1 and other Crb proteins. B, Alignments of the amino acid sequences of zebrafish Crb1, Crb2a, and Crb2b-lf. The last 37 amino acids in a red rectangle are the intracellular domains. C, The PDZ-binding motif and FERM-binding motif of the intracellular domains of Crb1, Crb2a, and Crb2b are underlined. Asterisks indicate the major variations of amino acids in the interval region between the PDZ-binding and FERM-binding motifs.