Identification of a putative Fe-S cluster assembly regulator in S. avermitilis. (A) Gene organization of the suf operons from different bacterial species (Escherichia coli, Bacillus subtilis, Synechocystis PCC 6083, Mycobacterium tuberculosis, and Streptomyces avermitilis). The genes with conserved functions are indicated with the same color. (B) Multiple sequence alignment of SufR homologs. Strictly conserved amino acids are highlighted in navy blue; underline, the HTH DNA-binding domain; *, conserved cysteine.