Table 2.

Multivariate Cox model for PFS and OS.

	PFS				OS
	HR	HR 95% CI		p value		HR 95% CI		p.value
		Lower	Upper		HR	Lower	Upper
CD9-CD63
CD9-CD63	1.111	1.001	1.224	0.048	1.23	1.07	1.4	0.0038
pT
T2 vs. T1	2.647	0.278	351.943	0.46	0.19	0	35.32	0.43
T3 vs. T1	6.478	0.784	843.189	0.093	0.73	0.05	105.38	0.85
T4 vs. T1	8.108	1.097	1034.889	0.037	2.35	0.27	310.28	0.52
Lymph node
N1 vs. N0	2.486	1.275	4.996	0.007	4.79	1.61	18.92	0.004
N2 vs. N0	5.171	2.533	10.711	< 0.001	10.43	3.4	41.79	< 0.001
EPCAM-CD63
Epcam-CD63	2.036	0.594	6.142	0.246	6.25	1.54	22.84	0.01
pT
T2 vs. T1	2.782	0.293	369.835	0.435	0.22	0	40.63	0.47
T3 vs. T1	6.583	0.795	857.115	0.09	0.71	0.05	102.21	0.84
T4 vs. T1	8.404	1.142	1071.917	0.032	2.55	0.29	335.14	0.47
Lymph node
N1 vs. N0	2.516	1.292	5.049	0.007	4.98	1.67	19.65	0.0031
N2 vs. N0	5.279	2.588	10.914	< 0.001	10.18	3.27	41.03	< 0.001

Abbreviation: PFS = progression free survival; OS = overall survival; HR = hazard ratio; CI = confidenced interval.

Abbreviation: AD = adenomas.

T = Primary tumour.

N = Regional lymph node.