Table 2.

The concentration of specific proteins in BeWo^Control-EVs, BeWo^{Matrix Only}-EVs, and BeWo^Matrix+TV-EVs (itTBC-EVs) inducing continuous HLA-G expression and secretion.

	Concentration (ng/ml)
Proteins	BeWoControl-EVs	BeWoMatrix Only-EVs	itTBC-EVs**
Progesterone	7.74 ± 0.96	13.51 ± 0.48	21.85 ± 3.49
sHLA-G*	8.79 ± 0.91	15.17 ± 0.48	29.18 ± 1.29
HLA-G5 & HLA-G6 (IU/ml)	26.74 ± 5.88	44.60 ± 0.22	89.74 ± 0.56
hCG	< Min	< Min	1.69 ± 0.07

*: soluble HLA-G1 & HLA-G5

**: The concentrations of each protein in itTBC-EVs obtained by 0.45-μm filter were higher than those in itTBC-EVs obtained by 0.22-μm filter (Supplemental Table 2).