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In vivo therapeutic efficacy of M-EV+Hybrid c(RGDm7)-LS-GE/DOX. (a) Tumour volume growth curves of A549 tumour-bearing nude mice injected with different treatments (n = 10). (b) Kaplan-Meier survival curve of nude mice after treatments (n= 9). (c) Photographs of mice bearing A549 subcutaneous tumours at the end of treatment. (d, e) TUNEL and CD31 staining of tumour sections. Scale bar: 200 μm.
