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Circulating placental growth factor (PlGF) concentrations gradually increase during pregnancy to reach a peak at approximately 30 weeks of gestation, coinciding with nonbranching angiogenesis of feto-placental vessels and maturation of the utero-placental circulation. PlGF concentrations (log scale) are on the basis of median values using the Triage PlGF test (Alere, San Diego) from Saffer et al. (11). Modified from reference 73, with permission.
