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. 2020 Jul 2;9(1):1786967. doi: 10.1080/20013078.2020.1786967

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© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of The International Society for Extracellular Vesicles.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — (A) Absolute quantification of miR-30c-5p levels as copy number in HCAECs after incubation with EV^{hnRNPU kd} compared to EV^{siRNA Control}, n = 6. (B) HCAEC migration upon treatment with EV^{hnRNPU kd} in a scratch-wound assay with representative images, n = 9/12. (C) HCAEC migration upon treatment with EV^{hnRNPU kd} in a transwell migration assay with representative images, n = 6. (D) qPCR-based analysis of 84 angiogenesis-related genes upon treatment with EV^{hnRNPU kd} compared to EV^{siRNA Control}. Top 10 upregulated and downregulated genes are displayed as 2^−ΔΔCT relative to EV^{siRNA Control} and GAPDH, n = 3. All data are presented as the mean ± SEM, *p < 0.05, **p < 0.01, ANOVA + Tukey post-hoc test for A, B, C, unpaired t-test for D.