Table 3.

Comparison miRNA expression and baseline characteristics of TB patients.

Features	No of Cases (%)	Fold change
		miR21	miR29a	miR31	miR146a	miR155
Age
<5 y	11 (36.7)	1.53 (0.72–2.35)	2.36 (1.16–2.67)	1.04 (0.78–2.58)	0.46 (0.37–0.67)	0.81 (0.71–1.53)
6 to 10 y	11 (36.7)	1.57 (1–2.36)	2.27 (1.03–2.67)	1.05 (0.84–1.48)	0.42 (0.33–0.63)	0.97 (0.89–1.76)
>10 y	8 (26.7)	1.54 (1.45–2.18)	2.29 (1.15–2.87)	1.28 (1.03–1.76)	0.45 (0.4–0.78)	1.29 (1.22–1.98)
p value		0.93	0.93	0.66	0.47	0.18
Gender
Male	17 (56.7)	1.51 (0.8–2.23)	2.36 (0.9–2.65)	0.94 (0.8–1.96)	0.51 (0.35–0.65)	1.29 (0.85–1.69)
Female	13 (43.3)	1.6 (1.3–2.3)	1.95 (1.2–2.73)	1.37 (1.08–1.67)	0.42 (0.4–0.7)	1.18 (0.76–1.50)
p value		0.2	0.97	0.34	0.87	0.57
LOA
< 5 days	15 (50)	1.53 (1.17–2.36)	2.34 (1.03–2.64)	1.04 (0.82–1.87)	0.55 (0.4–0.66)	1.31 (0.75–1.76)
>5 days	15 (50)	1.57 (1–2.11)	2.27 (1.16–3.01)	1.36 (0.92–1.58)	0.41 (0.33–0.45)	1.22 (0.92–1.37)
p value		0.64	0.67	0.81	0.09	0.79

Mann–Whitney U test was used to compare the expression levels of candidate miRNAs between the gender and loss of appetite. The Kruskal–Wallis test was used to analyze the difference in miRNAs expression levels between the different categories of age and Mann–Whitney U test was used to compare the expression levels of candidate miRNAs between the gender and loss of appetite of enrolled children. Data are median with IQR. TB, Tuberculosis; miRNA, Micro Ribonucleic Acid; IQR – Interquartile range; LOA – Loss of appetite; p-value, <0.5.