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. 2020 Aug 7;9(1):1800979. doi: 10.1080/20013078.2020.1800979

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© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of The International Society for Extracellular Vesicles.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — sEV characteristics. (a) Image of transmission electron microscope of sEVs isolated by min-SEC. (b) Western blot analysis of sEVs showing sEV markers as well as leukaemia associated antigens (LAA). (c) Increase of sEV production in plasma after chemotherapy. sEVs were isolated from series of plasma samples collected at diagnosis (d0) and consecutively at day5 and day10 after starting induction chemotherapy (d5 and d10, respectively). Levels of sEV proteins (n = 13, mean (green bar): d0: 49 ± 19 (mean±SEM), d5: 71 ± 20, d10: 83 ± 20, * p < 0.02, ** p < 0.001.