Figure 5.
The results of Gene Ontology (GO) analysis of proteins found in extracellular vesicles (EVs) derived from human neural stem cell-derived extracellular vesicles (hNSC-EVs). Figure (a) is a Venn diagram showing that out of 1,086 proteins detected in the hiPSC-NSC-EV preparations, 1,059 overlapped with the proteins in Vesiclepedia database. Figure (b) shows the involvement of EV-associated proteins in molecular, cellular and biological processes. The bar charts in C-G illustrate EV-associated proteins agrin (c), pentraxin 3 (d), hemopexin (e), galectin-3 binding protein (Gal-3BP; f), and nidogen-1 (g), validated through quantitative ELISAs.