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. 2020 Jul 13;9(1):1790874. doi: 10.1080/20013078.2020.1790874

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© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of The International Society for Extracellular Vesicles.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — MEx treatment ameliorates right ventricular hypertrophy (RVH) and improves functional exercise capacity. (a) Fulton’s Index measurements (ratio of right ventricle (RV) weight over left ventricle (LV) plus septum weight) and right ventricle-to-body weight ratio (RV:BW) (b) were undertaken to assess the degree of right ventricular hypertrophy (RVH), an index of pulmonary hypertension (PH). (c) Exercise capacity testing was carried out across all experimental groups to investigate the functional benefits of MEx. Mean ± SEM, n = 4–12 per group, *p < 0.05, ^#p < 0.001, ^$p < 0.0001 vs. HYRX group.