Table 3.
Clinical characteristics of study population by EUGR in weight based on the Intergrowth charts
| Non-EUGR (n = 612) | EUGR (n = 755) |
p value | |
|---|---|---|---|
| Gestational age (weeks) | 26.6 ± 1.0 | 26.2 ± 1.0 | < 0.001 |
| Birthweight (grams) | 891 ± 201.1 | 908.7 ± 178.9 | 0.087 |
| Birthweight z score | 0.0 ± 1.1 | 0.3 ± 0.8 | < 0.001 |
| Male sex | 275 (45.2) | 426 (57.0) | < 0.001 |
| Caesarean section | 428 (70.3) | 532 (71.2) | 0.719 |
| Maternal diabetes mellitus | 49 (8.1) | 48 (6.4) | 0.289 |
| Chorioamnionitis | 240 (44.9) | 285 (46.6) | 0.593 |
| PPROM | 246 (40.8) | 338 (45.6) | 0.086 |
| Oligohydramnios | 71 (13.0) | 80 (11.7) | 0.541 |
| Prenatal steroid | 488 (81.1) | 600 (82.1) | 0.541 |
| Multiple birth | 184 (30.2) | 220 (29.5) | 0.766 |
| Hypertension | 86 (14.1) | 57 (7.6) | < 0.001 |
| Apgar score 1 min | 4 ± 1.9 | 3.8 ± 1.7 | 0.102 |
| Apgar score 5 min | 6.3 ± 1.8 | 6.3 ± 1.7 | 0.714 |
| RDS | 587 (96.4) | 736 (98.5) | 0.013 |
| Treated PDA | 319 (52.4) | 461 (61.7) | 0.001 |
| Moderate to severe BPD | 267 (43.8) | 367 (49.1) | 0.056 |
| IVH ≥ grade 3 | 36 (5.9) | 105 (14.1) | < 0.001 |
| NEC | 20 (3.3) | 74 (9.9) | < 0.001 |
| ROP ≥ stage 2 | 126 (20.7) | 207 (27.8) | 0.003 |
| Sepsis | 163 (26.8) | 249 (33.3) | 0.009 |
| Duration of PN (days) | 29.5 ± 17.7 | 41.1 ± 23.0 | < 0.001 |
| Length of stay (days) | 90.4 ± 23.7 | 98.7 ± 23.8 | < 0.001 |
Values are expressed as number (%) or mean ± standard deviation. EUGR, extrauterine growth restriction; PPROM, preterm premature rupture of membrane; RDS, respiratory distress syndrome; PDA, patent ductus arteriosus; BPD, bronchopulmonary dysplasia; IVH, intraventricular haemorrhage; NEC, necrotizing enterocolitis; ROP, retinopathy of prematurity; PN, parenteral nutrition