Skip to main content
. 2020 Aug 24;2(9):e458–e467. doi: 10.1016/S2589-7500(20)30168-0

Figure 1.

Figure 1

Experimental design and registration of the NPS in infants and adults

(A) Stimuli were applied with a minimum interstimulus interval of 25 s across a range of intensities (64, 128, 256, or 512 mN) in a randomised order. Four stimulus intensities were used in adults (64, 128, 256, and 512 mN) and the two lowest stimulus intensities (64 and 128 mN) were used in infants. (B) The NPS was overlaid on the registered adult and infant templates, with both templates transformed into Montreal Neurological Institute template space (appendix p 2). Blue sections show anti-pain components of the NPS; red sections show pro-pain components of the NPS. NPS=neurologic pain signature.