Figure 2.

Intensity of the verbal pain report and quantification of the presence of six signatures in response to nociceptive input in the adult cohort (n=10)

(A) Mean NRS scores with increasing stimulus intensity. (B) Mean cosine similarity for six signatures, including the NPS and SIIPS1, and four control signatures, in response to nociceptive input. Vertical lines show SE. NRS=Numerical Rating Scale. NPS=neurologic pain signature. SIIPS1=stimulus intensity independent pain signature-1. PINES=picture-induced negative emotion signature. *Cosine similarity significantly higher than zero.