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. 2020 Aug;61(4):333–337. doi: 10.3325/cmj.2020.61.333

Table 1.

The median serum C-reactive protein to albumin ratio (CAR) before and three months after biological agent treatment


CAR median (interquartile range)

before treatment
after treatment P
Adalimumab (n = 65)
0.79 (0.52-1.14)
0.62 (0.36-1.02)
<0.001
Ustekinumab (n = 42)
0.90 (0.63-1.73)
0.82 (0.56-1.34)
0.006
Infliximab (n = 32)
1.08 (0.64-1.85)
0.84 (0.48-1.23)
0.007
Secukinumab (n = 18)
1.52 (1.01-3.04)
0.84 (0.62-0.99)
<0.001
All patients (n = 157)
0.97 (0.61-1.61)
0.73 (0.45-1.11)
<0.001
Patients with arthritis (n = 31)
1.01 (0.66-1.01)
0.80 (0.40-1.38)
0.002
Patients without arthritis (n = 126)
0.95 (0.58-1.59) 0.72 (0.47-1.06) <0.001