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. 2020 Aug;61(4):354–365. doi: 10.3325/cmj.2020.61.354

Table 2.

Results of generalized linear mixed model analysis

Target (analyzed parameter, ie, dependent variable) Fixed coefficient – neuropathology = schizophrenia
Fixed coefficient – neuropathology = control
Fixed effect (neuropathology) – P 1st random effect (subjects) – P 2nd random effect (neurons) – P
estimated mean standard error 95% confidence interval estimated mean standard error 95% confidence interval
Axon main trunk length
123.277
16.767
[92.560, 156.275]
63.962
14.532
[35.365, 90.280]
0.008
0.240
0.923
Axon main trunk surface
360.382
27.113
[307.025, 413.739]
196.182
18.064
[160.632, 231.732]
<0.001
0.601
0.884
Axon main trunk volume
101.416
8.786
[84.126, 118.707]
57.168
7.0184
[43.356, 70.980]
<0.001
0.330
0.948
Tortuosity
1.259
0.053
[1.155, 1.362]
1.185
0.052
[1.082, 1.287]
0.316
0.069
0.772
Base diameter
1.793
0.212
[1.376, 2.210]
1.558
0.208
[1.148, 1.968]
0.430
0.074
0.902
Average diameter 1.103 0.082 [0.942, 1.264] 1.084 0.081 [0.924, 1.243] 0.865 0.070 0.346