Fig 7. A comparison of experimental and simulated profiles demonstrates that ECM is sufficient to maintain the bent profile of the tissue.

(A) Experimental profile before adding Latrunculin A to inhibit actomyosin. The wing disc was stained with CellMask. Note that the imaging conditions required for live-imaging do not provide as fine resolution as for fixed images. (A’) Computational model after the bent profile of the wing disc is formed with higher levels of basal actomyosin contractility. (B) Experimental profile three hours after the addition of 4 μM Latrunculin to inhibit actomyosin. (B’) Computational profile of wing disc showing that bend profile of wing disc is preserved even after removal of basal actomyosin contraction.