Fig 2. TGD057-speicifc CD8 T cell IFNγ responses do not require the parasite’s export machinery.
The Δasp5 and Δmyr1 T. gondii strains listed were assayed for host CD8 T cell responses as previously described in Fig 1A. The IFNγ response at 48h, as analyzed by ELISA, is normalized to that of the clade D wildtype strain (ME49). Average of 4–6 experiments + SD is shown, each dot represents the results from one experiment. Statistical analysis was performed using one-way ANOVA with Bonferroni’s correction comparing mutant to parental strains; **** p ≤ 0.0001, ns non-significant.