Table 2.
The characteristics of WMH severity in patients with apathy or depression.
| Variable |
Total n = 141 |
Apathy n = 68 |
Non‐apathy n = 73 |
P‐value | P‐value 3 |
Depression n = 83 |
Non‐depression n = 58 |
P‐value | P‐value 3 |
|---|---|---|---|---|---|---|---|---|---|
| WMH Fazekas scale*, 1 | 2.16 ± 1.29 | 2.69 ± 1.33 | 1.66 ± 1.04 | <0.001* | ‐‐ | 2.28 ± 1.35 | 1.98 ± 1.21 | 0.164 | ‐‐ |
| WMH grade 2 | <0.001* | <0.001* | 0.194 | 0.072 | |||||
| Low, n (%) | 35 (24.82) | 8 (11.76) | 27 (36.99) | 17 (20.48) | 18 (31.03) | ||||
| Moderate, n (%) | 87 (61.70) | 44 (64.71) | 43 (58.90) | 52 (62.65) | 35 (60.34) | ||||
| High, n (%) | 19 (13.48) | 16 (23.53) | 3 (4.11) | 14 (20.59) | 5 (8.62) | ||||
| PVH grade 2 | <0.001* | <0.001* | 0.465 | 0.231 | |||||
| 0, n (%) | 17 (12.06) | 1 (1.47) | 16 (21.92) | 8 (9.64) | 9 (15.52) | ||||
| 1, n (%) | 87 (61.70) | 39 (57.35) | 48 (70.59) | 51 (61.45) | 36 (62.07) | ||||
| 2‐3, n (%) | 37 (26.24) | 28 (41.18) | 9 (13.24) | 24 (28.92) | 13 (22.41) | ||||
| DWMH grade 2 | <0.001* | <0.001* | 0.497 | 0.240 | |||||
| 0, n (%) | 31 (21.99) | 8 (11.76) | 23 (33.82) | 16 (19.28) | 15 (25.86) | ||||
| 1, n (%) | 91 (64.54) | 44 (64.71) | 47 (69.12) | 54 ( (65.06) | 37 (63.79) | ||||
| 2‐3, n (%) | 19 (13.48) | 16 (23.53) | 3 (4.41) | 13 (15.66) | 6 (10.34) |
Abbreviations: 2–3 = moderate; and 4–6 = high; DWMH, deep subcortical white matter hyperintensities; PVH was graded from 0 to 3: 0 = absence, 1 = “caps” or pencil‐thin lining, 2 = smooth “halo,” and 3 = irregular PVH extending into the deep white matter. Separately, DWMH was graded from 0 to 3 as well: 0 = absence, 1 = punctate foci, 2 = beginning confluence of foci, and 3 = large confluent areas. The severity of the WMH was graded according to the sum of the score for PVH (0–3) and the score for DWMH (0–3): 0–1 = low; PVH, periventricular hyperintensities; WMH, white matter hyperintensities.
Mann–Whitney U tests for continuous variables with a nonparametric distribution.
Chi‐squared tests for categorical variables. Values are expressed as a number (percentage).
p for linear‐by‐linear association
Statistically significant (P < 0.05).