Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 13;7(9):1681–1691. doi: 10.1002/acn3.51155

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals LLC on behalf of American Neurological Association

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Plasma NDEVs identified with TEM, NTA, and Western blotting. A single‐plasma NDEV (A) and clusters of plasma NDEVs (B) were measured with TEM. Scale bars equal 100 nm. An NTA plot (C) of size/concentration for plasma NDEVs derived from a patient with AD shows a high concentration. (D) ALIX, HSP90, and CD63 (EV markers) were present and calnexin (a marker for cellular components) was absent in plasma NDEVs enriched fraction samples. Abbreviations: NDEV, neuronally derived extracellular vesicle; TEM, transmission electron microscopy; NTA, nanoparticle tracking analysis; AD, Alzheimer’s disease.