. Author manuscript; available in PMC: 2020 Sep 9.

Published in final edited form as: Lancet Oncol. 2019 Oct 9;20(12):1710–1718. doi: 10.1016/S1470-2045(19)30493-0

Table 3:

Normative means, minimal clinically important differences, and baseline scores for patient-reported quality-of-life outcomes

	Baseline score mean (SD)	Normative mean^*	Absolute difference	Relative difference	Minimal clinically important difference^*
Pediatric Quality of Life Inventory	58·0 (20·1)	83·0	−25·0	−30%	4·36
Emotional functioning	61·0 (20·5)	80·9	−19·9	−25%	8·94
Social functioning	72·4 (20·3)	87·4	−15·0	−17%	8·36
School functioning	57·6 (22·7)	78·6	−21·0	−27%	9·12
Physical functioning	48·4 (27·1)	84·4	−36·0	−43%	6·66
Psychosocial health summary score	63·3 (18·6)	82·8	−19·5	−24%	5·30
Total score	58·0 (20·1)	83·0	−25·0	−30%	4·36
EQ-5D visual analogue scale	66·8 (21·8)	86·2	−19·4	−23%	7–10

Absolute differences were calculated as the difference between the mean baseline score and the normative mean. Relative differences were calculated as the absolute difference divided by the normative mean. EQ-5D=European Quality of Life-5 Dimensions questionnaire.

From literature point estimates.