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. Author manuscript; available in PMC: 2021 Mar 20.
Published in final edited form as: ACS Chem Biol. 2020 Jan 28;15(3):751–757. doi: 10.1021/acschembio.9b00992

Figure 3.

Figure 3.

A Cartoon representation of PPE (cyan) in complex with 1 (shown as grey sticks). B Comparison of 1 (grey) and 4 (PDB: 4GVU; orange) binding to PPE (cyan surface). The side chains of PPE residues Ser216 and Arg217 are shown as sticks. The additional hydrogen bond found in the PPE-1 complex structure is indicated by a dashed line.