TABLE I.
Patient Characteristics*
| Case No. | Age in Years, Sex | Location | Size (cm3) | Pathological Fracture | ASB | Dimensions of Exposed Articular Cartilage (mm) | Preop. KL Grade | KL Grade at Latest Follow-up | Contralateral KL Grade | Postop. Osteoarthritis | Bone-Modifying Agents | Follow-up Period (mo) | Additional Operation |
| 1 | 29, M | DF | 45 | No | 7% | 2 × 7 | 0 | 0 | 0 | – | – | 98 | Re-curettage |
| 2 | 30, M | DF | 36 | No | 3% | 3 × 6 | 0 | 3 | 0 | Secondary | – | 111 | OWHTO |
| 3 | 20, F | DF | 75 | Yes | 38% | 3 × 3 | 0 | 1 | 0 | Secondary | – | 102 | Hardware removal |
| 4 | 41, F | DF | 40 | No | 10% | 5 × 4 | 1 | 1 | 1 | – | – | 112 | – |
| 5 | 60, F | PT | 84 | No | 11% | 11 × 6 | 2 | 4 | 2 | Secondary | Denosumab | 112 | TKA |
| 6 | 33, F | PT | 90 | No | 27% | 2 × 4 | 1 | 1 | 1 | – | – | 117 | – |
| 7 | 35, F | DF | 66 | No | 17% | NA | 1 | 2 | 1 | Secondary | – | 128 | – |
| 8 | 43, M | PT | 39 | No | 10% | 0 | 1 | 1 | 1 | – | – | 139 | – |
| 9 | 28, M | DF | 57 | No | 17% | 5 × 6 | 0 | 0 | 0 | – | – | 66 | – |
| 10 | 59, F | DF | 96 | No | 21% | 8 × 9 | 1 | 3 | 1 | Secondary | Bisphosphonate | 69 | – |
| 11 | 27, M | DF | 66 | No | 8% | 0 | 0 | 0 | 0 | – | – | 140 | – |
| 12 | 31, F | PT | 66 | No | 42% | 5 × 6 | 0 | 0 | 0 | – | – | 141 | – |
| 13 | 63, F | PT | 15 | No | 13% | NA | 1 | 2 | 2 | Age-related | Bisphosphonate | 155 | – |
| 14 | 58, M | DF | 80 | No | 12% | NA | 1 | 1 | 1 | – | – | 165 | – |
| 15 | 26, F | PT | 42 | No | 18% | 0 | 0 | 0 | 0 | – | – | 172 | – |
| 16 | 33, F | DF | 32 | No | 10% | NA | 0 | 0 | 0 | – | – | 169 | – |
| 17 | 61, F | DF | 60 | No | 17% | NA | 1 | 2 | 2 | Age-related | – | 193 | – |
| 18 | 28, F | DF | 54 | No | 53% | 7 ×9 | 0 | 0 | 0 | – | – | 205 | – |
| 19 | 20, M | PT | 36 | No | 19% | 9 × 9 | 0 | 0 | 0 | – | Denosumab | 104 | – |
*
ASB = amount of subchondral bone involvement, preop. = preoperative, postop. = postoperative, DF = distal aspect of the femur, OWHTO = open-wedge high tibial osteotomy, PT = proximal aspect of the tibia, TKA = total knee arthroplasty, and NA = not applicable.