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. 2020 Sep 10;27(8):1268–1277. doi: 10.1093/jamia/ocaa124

Table 3.

Counts and maximum standardized difference per database. T = lisinopril, C = amlodipine, Outcome = angioedema, Max std. diff. = Maximum absolute standardized difference of means between T and C

Subjects
Patient years
Outcomes
Covariate count Max std. diff.
Source T C T C T C Before After
CCAE 647 212 183 776 465 516 126 173 671 97 9765 0.407 0.029
MDCD 59 897 26 525 29 464 11 187 150 26 12 703 0.526 0.048
MDCR 73 821 32 375 61 864 28 107 99 18 11 217 0.363 0.029
Optum 447 905 143 079 340 148 107 631 475 88 11 903 0.432 0.028
PanTher 651 707 201 527 243 121 71 438 236 44 10 548 0.425 0.022
Total 1 884 874 590 945 1 146 421 348 158 1646 279

Abbreviations: CCAE, Commercial Claims and Encounters; MDCD, Multi-state Medicaid; MDCR, Medicare Supplemental Beneficiaries; Optum, Optum ClinFormatics; PanTher, Optum deidentified Electronic Health Record Dataset.