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. 2020 Sep 10;144:110259. doi: 10.1016/j.mehy.2020.110259

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Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 1 — Effect of electric impulse on coronavirus. Electric impulse may damage the viral envelope by disrupting the membrane. Further, by modulating viral spike protein it may hamper the binding of virus to the host cell receptor. Due to damaged viral envelope there may be increase in drug permeability through damaged/ruptured viral envelop which may enhance drug efficacy. Due to the electric current stimulus, there could be change in the viral membrane protein which may cause resistance to certain drugs. By implementing electric current stimulus in such cases, the probability of drug resistance can be reduced.