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. 2020 Sep 9;11(9):731. doi: 10.1038/s41419-020-02952-6

Fig. 5. miR-210-3p confers growth-advantage and anti-apoptotic activity in TNBC by targeting GPD1L and CYGB.

Fig. 5

a The plate colony formation ability of MDA-MB-231 and Hs578T cells after transfection with control or miR-210-3p mimics. b The effect of miR-210-3p on in vivo tumor growth was studied by a subcutaneous xenograft model. c After serum starvation for 48 h, cell apoptosis in control or miR-210-3p mimic-transfected MDA-MB-231 and Hs578T cells was measured by Caspase-3/7 activity. d The plate colony formation ability of MDA-MB-231 and Hs578T cells after ectopic expression of GPD1L or CYGB. e After serum starvation for 24 h, cell apoptosis status in pcDNA3.1-vector, GPD1L-overexpressing or CYGB-overexpressing MDA-MB-231 and Hs578T cells was measured by Caspase-3/7 activity. f Measurement of the effects of miR-210-3p on cell proliferation and cell apoptosis upon overexpression of GPD1L or CYGB in MDA-MB-231 and Hs578T cells. *p < 0.05; **p < 0.01; ***p < 0.001.