Table 1.
Causes of hypertriglyceridemia.
| Primary Causes | |
| Genetic syndromes | Familial hypertriglyceridemia |
| Familial combined hyperlipidemia | |
| Lipoprotein lipase deficiency | |
| Apolipoprotein C-II deficiency | |
| Apolipoprotein AV deficiency | |
| Dysbetalipoproteinemia | |
| Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 (GPIHBP1) deficiency |
|
| Secondary Causes | |
| Disease | Metabolic syndrome |
| Hypothyroidism | |
| Diabetes mellitus | |
| Central obesity | |
| Renal diseases | |
| Nephrotic syndrome | |
| Autoimmune disorders (e.g. lupus) | |
| HIV-associated dyslipidemia | |
| Pregnancy (third trimester) | |
| Medications | Non-selective beta blockers |
| Thiazides | |
| Corticosteroids | |
| Tamoxifen | |
| Raloxifene | |
| Oral estrogens | |
| Protease inhibitors | |
| Retinoic acid | |
| Isotretinoin | |
| Sirolimus | |
| l-asparaginase | |
| Bile acid resins | |
| Phenothiazines | |
| Second-generation antipsychotics | |
| Immunosuppressants | |
| Diet | Excess alcohol |
| Positive-energy balanced diet with saturated fat or high glycemic index/load content | |
Republished with permission of Bentham Science Publishers, from Hypertriglyceridemia - common causes, prevention and treatment strategies, Rygiel K, Curr Cardiol Rev 2018[15]; permission conveyed through Copyright Clearance Center, Inc.