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MAGE procedure. The red squares represent the cells, the black circles represent the ptkRED plasmid, and Exo, Bet and gam are the gene sequences of the enzymes on the plasmid. The yellow and blue circles represent the bacterial genome, with the red portion representing the target engineered gene sequence. Exo, exonuclease; Bet, phage recombination protein Bet; gam, host-nuclease inhibitor protein Gam.
