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The effect of RN486 on the ATPase activity of ABCB1. Different concentrations (0–40 μM) of RN486 affected the ATP hydrolysis process, which mediated by ATPase of ABCB1. The inset graph demonstrates the effect of 0–10 μM RN486 on the ATPase activity of ABCB1. Data are mean ± SD of three independent assays.
