Table 3.
COVID-19 complications
| Characteristics | Total (n = 128) | Deaths caused by SARS-CoV-2 infection (n = 109) | Death with SARS-CoV-2 infection (n = 19) | p |
|---|---|---|---|---|
| Days in hospital until death, median (IQR), days | 6 (3–10) | 7 (3–13) | 5 (1–9) | 0.035 |
| ARDS | 93 (77%) | 93 (85%) | 0 (0%) | < 0.001 |
| Hyperinflammation | 93 (77%) | 86 (79%) | 7 (37%) | < 0.001 |
| Septic shock | 12 (9%) | 11 (10%) | 1 (5%) | 0.505 |
| Pulmonary embolism | 3 (2%) | 3 (3%) | 0 (0%) | 0.464 |
| Place of death | ||||
| Hospital ward | 102 (80%) | 83 (76%) | 19 (100%) | |
| Intensive care unit | 26 (20%) | 26 (24%) | 0 (0%) | 0.013 |
| Main cause of death | ||||
| ARDS or severe lung injury (> 50% lung involvement in X-ray) caused by COVID | 104 (81%) | 104 (95%) | 0 (0%) | < 0.001 |
| Pulmonary thromboembolism | 2 (2%) | 2 (2%) | 0 (0%) | |
| Sepsis shock due to COVID | 3 (2%) | 3 (3%) | 0 (0%) | |
| Sepsis caused by bacterial infection without lung injury | 3 (3%) | 0 (0%) | 3 (16%) | |
| Wasting associated with age | 10 (8%) | 0 (0%) | 10 (53%) | |
| Heart failure without acute cardiac injury | 2 (2%) | 0 (0%) | 2 (11%) | |
| Kidney failure without lung injury or shock | 2 (2%) | 0 (0%) | 2 (11%) | |
| Bronchoaspiration | 1 (1%) | 0 (0%) | 1 (5%) | |
| Gastrointestinal bleeding | 1 (1%) | 0 (9%) | 1 (5%) | |
| Week of death | ||||
| 18–24 March | 11 (9%) | 7 (6%) | 4 (21%) | 0.042 |
| 25–31 March | 37 (29%) | 31 (28%) | 6 (32%) | |
| 1–7 April | 26 (20%) | 22 (20%) | 4 (21%) | |
| 8–14 April | 21 (16%) | 18 (17%) | 3 (16%) | |
| 15–21 April | 17 (13%) | 16 (15%) | 1 (5%) | |
| > 21 April | 16 (13%) | 15 (14%) | 1 (5%) | |
Bold indicate p values that achieve statistical significance (p < 0.05)
Deaths caused by SARS-CoV-2 infection: patients whose death was caused directly by SARS-CoV-2 infection. Death with SARS-CoV-2 infection: patients where SARS-CoV-2 acted as a precipitating factor to decompensate other chronic or acute pathologies that were the main cause of death
ARDS acute respiratory distress syndrome