FIGURE 1.

Diversity of cathelicidin peptides among vertebrate groups. Circular bar plots show the distribution of length, charge and proportion of hydrophobic amino acids among representative vertebrate cathelicidin peptides (see Supplementary Table S1). The order of sequences in each group is sorted by peptide length. Physico-chemical properties were computed using the Peptides package v2.4.2 (Osorio et al., 2015) in R v4.0.0 (R Core Team, 2020). Net charge was predicted using the Bjellqvist’s pK scale implemented in the Peptides package. Animal silhouettes were created by: NASA (mammals; human), Juan Carlos Jerí (birds; shearwater), uncredited (reptiles; turtle), Will Booker (amphibians; tree frog) and Felix Vaux (fish), and downloaded from http://phylopic.org/.