Table 1.
List of Sequences used to construct phylogenetic trees.
| Hormone | Organism | Phylum | Class | Order | Accession number |
|---|---|---|---|---|---|
| CRF FAMILY | |||||
| CRF | Xenopus laevis (African clawed frog) | Chordata | Amphibia | Anura | NM_001172210 |
| CRF | Rana sylvatica (Wood frog) | Chordata | Amphibia | Anura | HQ630608 |
| CRF | Gallus gallus (Chicken) | Chordata | Aves | Galliformes | NM_001123031 |
| CRF | Columba livia (Rock pigeon) | Chordata | Aves | Columbiformes | XM_005506466 |
| CRF | Danio rerio (Zebrafish) | Chordata | Actinopterygii | Cypriniformes | JN859047 |
| CRF | Salmo salar (Atlantic salmon) | Chordata | Actinopterygii | Salmoniformes | NM_001141590 |
| CRF | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | NM_205769 XM_357335 |
| CRF | Canis lupus familiaris (Dog) | Chordata | Mammalia | Carnivora | NM_001014278 XM_544106 |
| CRF | Petromyzon marinus (Sea lamprey) | Chordata | Cephalaspidomorphi | Petromyzontiformes | Endsin et al. (35) |
| CRF | Latimeria chalumnae (Coelacanth) | Chordata | Sarcopterygii | Coelacanthiformes | XM_006009123 |
| CRF | Chrysemys picta bellii (Western painted turtle) | Chordata | Reptilia | Testudines | XM_005288085 |
| CRF | Asterias rubens (Common starfish) | Echinodermata | Asteroidea | Forcipulatida | Semmens et al. (36) |
| CRF | Ciona intestinalis (Sea tunicate) | Urochordata | Ascidiacea | Enterogona | Lovejoy and Barsyte-Lovejoy, (37) |
| TCN | Oryzias latipes (Japanese rice fish) | Chordata | Actinopterygii | Beloniformes | BAR90710.1 |
| SVG | Pachymedusa dacnicolor (Mexican tree frog) | Chordata | Amphibia | Anura | FR846380 |
| SVG | Phyllomedusa sauvagii | Chordata | Amphibia | Anura | AAY21509.1 |
| UCN | Pseudopodoces humilis (Tibetan ground-tit) | Chordata | Aves | Passeriformes | XM_005532743 |
| UCN | Melopsittacus undulatus (Budgerigar) | Chordata | Aves | Psittaciformes | XM_005140144 |
| UCN | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | NM_021290 |
| UCN | Canis lupus familiaris (Dog) | Chordata | Mammalia | Carnivora | XM_848667 |
| UCN | Alligator mississippiensis (American alligator) | Chordata | Reptilia | Crocodylia | XM_006273603 |
| UCN2 | Sus scrofa (Pig) | Chordata | Mammalia | Artiodactyla | XM_003132185 |
| UCN2 | Bos taurus (Cattle) | Chordata | Mammalia | Artiodactyla | XM_005223016 |
| UCN2 | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | NM_145077 XM_910603 |
| UCN2 | Canis lupus familiaris (Dog) | Chordata | Mammalia | Carnivora | XM_005632587 |
| UCN2 | Oryzias latipes (Japanese rice fish) | Chordata | Actinopterygii | Beloniformes | NP_001121991.1 |
| UCN3 | Anas platyrhynchos (Mallard) | Chordata | Aves | Anseriformes | XM_005014551 |
| UCN3 | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | NM_031250 |
| UCN3 | Bos taurus (Cattle) | Chordata | Mammalia | Artiodactyla | NM_001076527 |
| UCN3 | Alligator sinensis (Chinese alligator) | Chordata | Reptilia | Crocodylia | XM_006035307 |
| UCN3 | Petromyzon marinus (Sea lamprey) | Chordata | Cephalaspidomorphi | Petromyzontiformes | Endsin et al. (35) |
| UCN3 | Oryzias latipes (Japanese rice fish) | Chordata | Actinopterygii | Beloniformes | NP_001121992.1 |
| UI | Oncorhynchus mykiss (Rainbow trout) | Chordata | Actinopterygii | Salmoniformes | NM_001124343 |
| UI | Danio rerio (Zebrafish) | Chordata | Actinopterygii | Cypriniformes | NM_001030180 XM_687090 |
| UI | Carassius auratus (Goldfish) | Chordata | Actinopterygii | Cypriniformes | AF129115 |
| UI | Petromyzon marinus (Sea lamprey) | Chordata | Cephalaspidomorphi | Petromyzontiformes | Endsin et al. (35) |
| DH 31 | Drosophila melanogaster (Fruit fly) | Arthropoda | Insecta | Diptera | NM_078790 |
| DH 40 | Bombyx mori (Domestoc silkworm) | Arthropoda | Insecta | Lepidoptera | AB298934 |
| DH 31 | Rhodnius prolixus (Assassin bug) | Arthropoda | Insecta | Hemiptera | HM030716 |
| DH | Balanus amphitrite (Barnacle) | Arthropoda | Maxillopoda | Sessilia | JQ864196 |
| CALCITONIN FAMILY | |||||
| CALC | Gallus gallus (Chicken) | Chordata | Aves | Galliformes | X03012 |
| CALC | Bos taurus (Cattle) | Chordata | Mammalia | Artiodactyla | AB462435 |
| CALC | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | X97991 |
| CALC | Alligator sinensis (Chinese alligator) | Chordata | Reptilia | Crocodylia | XM_006018232 |
| CALC | Chrysemys picta bellii (Western painted turtle) | Chordata | Reptilia | Testudines | XM_005303304 |
| CALC | Ciona intestinalis (Sea tunicate) | Urochordata | Ascidiacea | Enterogona | AB485672 |
| CALC | Equus caballus (Horse) | Chordata | Mammalia | Perissodactyla | AF249307 |
| CALC | Chinchilla lanigera (Long-tailed chinchilla) | Chordata | Mammalia | Rodentia | XP_005380394.1 |
| CALC | Spermophilus tridecemlineatus (Squirrel) | Chordata | Mammalia | Rodentia | XM_005326775 |
| CGRP1 | Gallus gallus (Chicken) | Chordata | Aves | Galliformes | NM_001113708 |
| CGRP1 | Danio rerio (Zebrafish) | Chordata | Actinopterygii | Cypriniformes | NM_001002471 |
| CGRP1 | Salmo salar (Atlantic salmon) | Chordata | Actinopterygii | Salmoniformes | NM_001146580 |
| CGRP1 | Bos taurus (Cattle) | Chordata | Mammalia | Artiodactyla | NM_001076340 |
| CGRP1 | Canis lupus familiaris (Dog) | Chordata | Mammalia | Carnivora | NM_001003266 |
| CGRP2 | Callorhinchus milii (Elelphant shark) | Chordata | Chondrichthyes | Chimaeriformes | XM_007887527 |
| CGRP2 | Bos taurus (Cattle) | Chordata | Mammalia | Artiodactyla | NM_001134662 |
| CGRP2 | Canis lupus familiaris (Dog) | Chordata | Mammalia | Carnivora | NM_001002948 |
| CGRP2 | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | NM_054084 |
| CGRP2 | Sus scrofa (Pig) | Chordata | Mammalia | Artiodactyla | NM_001102473 |
| CGRP2 | Oryzias latipes (Japanese rice fish) | Chordata | Actinopterygii | Beloniformes | NM_001104894 |
| Amylin | Columba livia (Rock pigeon) | Chordata | Aves | Columbiformes | XM_005504095 |
| Amylin | Gallus gallus (Chicken) | Chordata | Aves | Galliformes | NM_205397 |
| Amylin | Carassius auratus (Goldfish) | Chordata | Actinopterygii | Cypriniformes | EU000530 |
| Amylin | Latimeria chalumnae (Coelacanth) | Chordata | Sarcopterygii | Coelacanthiformes | XM_005998862 |
| Amylin | Bos taurus (Cattle) | Chordata | Mammalia | Artiodactyla | NM_001195038 |
| Amylin | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | NM_010491 |
| Amylin | Sus scrofa (Pig) | Chordata | Mammalia | Artiodactyla | XM_003126437 |
| Amylin | Alligator mississippiensis (American alligator) | Chordata | Reptilia | Crocodylia | XM_006270879 |
| ADM | Xenopus tropicalis (Western clawed frog) | Chordata | Amphibia | Anura | XM_002936741 |
| ADM | Columba livia (Rock pigeon) | Chordata | Aves | Columbiformes | XM_005499377 |
| ADM | Carassius auratus (Goldfish) | Chordata | Actinopterygii | Cypriniformes | EU000533 |
| ADM | Latimeria chalumnae (Coelacanth) | Chordata | Sarcopterygii | Coelacanthiformes | XM_005989689 |
| ADM | Sus scrofa (Pig) | Chordata | Mammalia | Artiodactyla | D14875 |
| ADM | Bos taurus (Cattle) | Chordata | Mammalia | Artiodactyla | NM_173888 |
| ADM | Canis lupus familiaris (Dog) | Chordata | Mammalia | Carnivora | AB191461 |
| ADM | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | NM_009627 |
| ADM2 | Xenopus tropicalis (Western clawed frog) | Chordata | Amphibia | Anura | XM_002939371 |
| ADM2 | Gallus gallus (Chicken) | Chordata | Aves | Galliformes | XM_004937395 |
| ADM2 | Latimeria chalumnae (Coelacanth) | Chordata | Sarcopterygii | Coelacanthiformes | XM_006013419 |
| ADM2 | Poecilia formosa (Amazon molly) | Chordata | Actinopterygii | Cyprinodontiformes | XM_007545759 |
| ADM2 | Canis lupus familiaris (Dog) | Chordata | Mammalia | Carnivora | XM_843399 |
| ADM2 | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | AB121035 |
| ADM2 | Alligator mississippiensis (American alligator) | Chordata | Reptilia | Crocodylia | XM_006275255 |
| SECRETIN FAMILY | |||||
| GHRH | Xenopus laevis (African clawed frog) | Chordata | Amphibia | Anura | NM_001096728 |
| GHRH | Gallus gallus (Chicken) | Chordata | Aves | Galliformes | NM_001040464 |
| GHRH | Callorhinchus milii (Elelphant shark) | Chordata | Chondrichthyes | Chimaeriformes | XM_007885752 |
| GHRH | Danio rerio (Zebrafish) | Chordata | Actinopterygii | Cypriniformes | NM_001080092 |
| GHRH | Bos taurus (Cattle) | Chordata | Mammalia | Artiodactyla | NM_178325 |
| GHRH | Canis lupus familiaris (Dog) | Chordata | Mammalia | Carnivora | NM_001290112 |
| GHRH | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | NM_010285 |
| GHRH | Sus scrofa (Pig) | Chordata | Mammalia | Artiodactyla | NM_001195118 |
| GHRH | Anolis carolinensis (Green anole) | Chordata | Reptilia | Squamata | XM_003225298 |
| GHRH | Chrysemys picta bellii (Western painted turtle) | Chordata | Reptilia | Testudines | XM_005295322 |
| GIP | Xenopus laevis (African clawed frog) | Chordata | Amphibia | Anura | NM_001097922 |
| GIP | Gallus gallus (Chicken) | Chordata | Aves | Galliformes | NM_001080104 |
| GIP | Danio rerio (Zebrafish) | Chordata | Actinopterygii | Cypriniformes | NM_001080059 |
| GIP | Bos taurus (Cattle) | Chordata | Mammalia | Artiodactyla | NM_001166605 |
| GIP | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | NM_008119 |
| GIP | Sus scrofa (Pig) | Chordata | Mammalia | Artiodactyla | NM_001287408 |
| GIP | Alligator mississippiensis (American alligator) | Chordata | Reptilia | Crocodylia | XM_006277905 |
| GIP | Chelonia mydas (Green sea turtle) | Chordata | Reptilia | Testudines | XM_007061917 |
| GCG | Gallus gallus (Chicken) | Chordata | Aves | Galliformes | NM_205260 |
| GCG | Callorhinchus milii (Elelphant shark) | Chordata | Chondrichthyes | Chimaeriformes | XM_007889848 |
| GCG | Bos taurus (Cattle) | Chordata | Mammalia | Artiodactyla | NM_173916 |
| GCG | Sus scrofa (Pig) | Chordata | Mammalia | Artiodactyla | NM_214324 |
| GCG | Ovis aries (Sheep) | Chordata | Mammalia | Cetartiodactyla | XM_004004659 |
| GCG | Alligator mississippiensis (American alligator) | Chordata | Reptilia | Crocodylia | XM_006277994 |
| GCG | Poecilia formosa (Amazon molly) | Chordata | Actinopterygii | Cyprinodontiformes | XM_007546594 |
| GCG | Latimeria chalumnae (Coelacanth) | Chordata | Sarcopterygii | Coelacanthiformes | XM_006004345 |
| PACAP | Xenopus laevis (African clawed frog) | Chordata | Amphibia | Anura | AF187877 |
| PACAP | Gallus gallus (Chicken) | Chordata | Aves | Galliformes | AY956323 |
| PACAP | Ctenopharyngodon idella (Grass carp) | Chordata | Actinopterygii | Cypriniformes | EF592488 |
| PACAP | Bos taurus (Cattle) | Chordata | Mammalia | Artiodactyla | AY924308 |
| SCT | Gallus gallus (Chicken) | Chordata | Aves | Galliformes | NM_001024833 |
| SCT | Taeniopygia guttata (Zebra finch) | Chordata | Aves | Passeriformes | NM_001256233 |
| SCT | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | X73580 |
| SCT | Sus scrofa (Pig) | Chordata | Mammalia | Artiodactyla | XM_003122391 |
| SCT | Equus caballus (Horse) | Chordata | Mammalia | Perissodactyla | XM_003362642 |
| SCT | Chelonia mydas (Green sea turtle) | Chordata | Reptilia | Testudines | XM_007060911 |
| VIP | Xenopus laevis (African clawed frog) | Chordata | Amphibia | Anura | NM_001085714 |
| VIP | Columba livia (Rock pigeon) | Chordata | Aves | Columbiformes | XM_005507654 |
| VIP | Gallus gallus (Chicken) | Chordata | Aves | Galliformes | NM_205366 |
| VIP | Danio rerio (Zebrafish) | Chordata | Actinopterygii | Cypriniformes | NM_001114553 |
| VIP | Bos taurus (Cattle) | Chordata | Mammalia | Artiodactyla | AF503910 |
| VIP | Canis lupus familiaris (Dog) | Chordata | Mammalia | Carnivora | XM_005615524 |
| VIP | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | NM_011702 |
| VIP | Sus scrofa (Pig) | Chordata | Mammalia | Artiodactyla | NM_001195233 |
| VIP | Alligator mississippiensis (American alligator) | Chordata | Reptilia | Crocodylia | XM_006265239 |
| OTHER | |||||
| NPY | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | EDK98613.1 |
| NPY | Danio rerio (Zebrafish) | Chordata | Actinopterygii | Cypriniformes | AAI62071.1 |
| NPY | Carassius auratus (Goldfish) | Chordata | Actinopterygii | Cypriniformes | AAA49186.1 |
| NPY | Rattus norvegicus (Norway rat) | Chordata | Mammalia | Rodentia | NP_036746.1 |
| NPY | Gallus gallus (Chicken) | Chordata | Aves | Galliformes | NP_990804.1 |
| NPY | Xenopus laevis (African clawed frog) | Chordata | Amphibia | Anura | AAH80115.1 |
| NPY | Ovis aries (Sheep) | Chordata | Mammalia | Cetartiodactyla | NP_001009452.1 |
| NPY | Bos taurus (Cattle) | Chordata | Mammalia | Artiodactyla | ACH61954.1 |
| NPY | Homo sapiens (Human) | Chordata | Mammalia | Primate | NP_000896.1 |
| NPY | Columba livia (Rock pigeon) | Chordata | Aves | Columbiformes | NP_001269740.1 |
| NPY | Pseudopodoces humilis (Ground tit) | Chordata | Aves | Passeriformes | XP_005518939.1 |
| NPY | Callorhinchus milii (Elelphant shark) | Chordata | Chondrichthyes | Chimaeriformes | ACF22970.1 |
| NPY | Chrysemys picta bellii (Western painted turtle) | Chordata | Reptilia | Testudines | XP_005290923.1 |
| INS | Ciona intestinalis (Sea tunicate) | Urochordata | Ascidiacea | Enterogona | NP_001123204.1 |
| INS | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | ABF48502.1 |
| INS | Rattus norvegicus (Norway rat) | Chordata | Mammalia | Rodentia | AAA41439.1 |
| INS | Ictidomys tridecemlineatus (Ground squirrel) | Chordata | Mammalia | Rodentia | AAK72558.1 |
| INS | Ovis aries (Sheep) | Chordata | Mammalia | Cetartiodactyla | AAB60625.1 |
| INS | Gallus gallus (Chicken) | Chordata | Aves | Galliformes | NP_990553.1 |
| INS | Columba livia (Rock pigeon) | Chordata | Aves | Columbiformes | EMC88047.1 |
| INS | Pseudopodoces humilis (Ground tit) | Chordata | Aves | Passeriformes | XP_005522396.1 |
| INS | Callorhinchus milii (Elelphant shark) | Chordata | Chondrichthyes | Chimaeriformes | XP_007902984.1 |
| INS | Danio rerio (Zebrafish) | Chordata | Actinopterygii | Cypriniformes | NP_571131.1 |
| INS | Carassius auratus (Goldfish) | Chordata | Actinopterygii | Cypriniformes | ALO24192.1 |
| INS | Salmo salar (Atlantic salmon) | Chordata | Actinopterygii | Salmoniformes | ACI69187.1 |
| INS | Latimeria chalumnae (Coelacanth) | Chordata | Sarcopterygii | Coelacanthiformes | XP_006008147.1 |
| INS | Poecilia formosa (Amazon molly) | Chordata | Actinopterygii | Cyprinodontiformes | XP_016521686.1 |
| INS | Chrysemys picta bellii (Western painted turtle) | Chordata | Reptilia | Testudines | XP_005312438.1 |
| TCAP1 | Xenopus laevis (African clawed frog) | Chordata | Amphibia | Anura | XP_017951867.1 |
| TCAP1 | Callorhinchus milii (Elelphant shark) | Chordata | Chondrichthyes | Chimaeriformes | XP_007893009.1 |
| TCAP | Caenorhabditis elegans (Roundworm) | Nematoda | Secernentea | Rhabditida | NM_171175 |
| TCAP | Drosophila melanogaster (Fruit fly) | Arthropoda | Insecta | Diptera | NP_001097661 |
| TCAP1 | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | NP_035985.2 |
| TCAP1 | Danio rerio (Zebrafish) | Chordata | Actinopterygii | Cypriniformes | XP_691552.5 |
| TCAP1 | Columba livia (Rock pigeon) | Chordata | Aves | Columbiformes | EMC88689.1 |
| TCAP2 | Xenopus laevis (African clawed frog) | Chordata | Amphibia | Anura | XP_012815129.1 |
| TCAP2 | Callorhinchus milii (Elelphant shark) | Chordata | Chondrichthyes | Chimaeriformes | XP_007900206.1 |
| TCAP2 | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | NP_035986.3 |
| TCAP2 | Danio rerio (Zebrafish) | Chordata | Actinopterygii | Cypriniformes | XP_017208443.1 |
| TCAP2 | Columba livia (Rock pigeon) | Chordata | Aves | Columbiformes | EMC78205.1 |
| TCAP3 | Xenopus laevis (African clawed frog) | Chordata | Amphibia | Anura | NP_001096158 |
| TCAP3 | Callorhinchus milii (Elelphant shark) | Chordata | Chondrichthyes | Chimaeriformes | XP_007894102.1 |
| TCAP3 | Strongylocentrotus purpuratus (Sea urchin) | Echinodermata | Echinoidea | Echinoidea | XM_001180001 |
| TCAP3 | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | NP_035987.3 |
| TCAP3 | Danio rerio (Zebrafish) | Chordata | Actinopterygii | Cypriniformes | NP_571043.1 |
| TCAP3 | Columba livia (Rock pigeon) | Chordata | Aves | Columbiformes | XP_005505621.1 |
| TCAP4 | Xenopus laevis (African clawed frog) | Chordata | Amphibia | Anura | NP_001096158.1 |
| TCAP4 | Callorhinchus milii (Elelphant shark) | Chordata | Chondrichthyes | Chimaeriformes | XP_007900970.1 |
| TCAP4 | Mus musculus (House mouse) | Chordata | Mammalia | Rodentia | NP_001297689.1 |
| TCAP4 | Danio rerio (Zebrafish) | Chordata | Actinopterygii | Cypriniformes | NP_571044.2 |
| TCAP4 | Columba livia (Rock pigeon) | Chordata | Aves | Columbiformes | XP_005500626.1 |