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Schematic representation of human placenta showing anchoring villi attached to maternal decidua. Extravillous trophoblasts depart from the villi and invade the decidua surrounding the spiral arteries. Other cells enter the lumen of the arteries as endovasculat trophoblasts and partially replace lining endothelial cells. C1q produced by trophoblasts is used to promote their migration and interaction with endothelial cells.
