Table 4.
Dose dependent therapeutic efficacy of YAP/TAZ in different hormone receptor (HR) status.
HR status | YAP/TAZ status | Therapy response | |||||||
---|---|---|---|---|---|---|---|---|---|
RTDI ≤ 85% | RTDI >85% | ||||||||
ORR (%) | P | pCR | P | ORR (%) | P | pCR | P | ||
Positive | ≤0.5 | 78.47 | 0.691 | 6/35 | 0.154 | 96.34 | 0.047 | 29/99 | 0.038 |
>0.5 | 66.10 | 9/40 | 80.67 | 11/66 | |||||
Negative | ≤0.5 | 82.66 | 0.352 | 4/22 | 0.098 | 99.01 | 0.011 | 36/70 | 0.005 |
>0.5 | 74.34 | 7/27 | 77.06 | 2/38 |