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. 2020 Aug;9(4):1029–1040. doi: 10.21037/tlcr-19-321

Figure 2.

Figure 2

mRNA expressions of FOXM1, its downstream and upstream molecules. (A) A scheme of FOXM1 and part of its downstream targets involved in cancer. (B) mRNA expression of FOXM1. (C,D,E,F,G) mRNA expressions of FOXM1 downstream targets CCNB1, VEGFA, PLK4, MMP9 and STMN1. (H,I,J) mRNA expressions of FOXM1 upstream molecules E2F1, ESR1 and FOXO3. P value, Jonckheere-Terpstra test. L, lepidic predominant ADC; P, papillary predominant ADC; A, acinar predominant ADC; M, micropapillary predominant ADC; S, solid predominant ADC.