Table 3. Multivariable Cox analysis of LRFS and OS.
| Variables | LRFS | OS | |||
|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | ||
| Age (years) | |||||
| <63 | 1.000 | 1.000 | |||
| ≥63 | 4.254 (1.563–11.574) | 0.005 | 1.793 (1.097–2.929) | 0.020 | |
| Primary site | – | – | |||
| Non-CRC | 1.000 | ||||
| CRC | 2.611 (1.019–6.693) | 0.046 | |||
| BED10 of PTV min dose (Gy) | – | – | |||
| <76.6 | 1.000 | ||||
| ≥76.6 | 0.238 (0.069–0.819) | 0.023 | |||
| Sex | – | – | |||
| Male | 1.000 | ||||
| Female | 0.434 (0.236–0.796) | 0.007 | |||
| Tumor diameter (cm) | – | – | |||
| <1.35 | 1.000 | ||||
| ≥1.35 | 0.457 (0.275–0.758) | 0.002 | |||
| Histology | – | – | |||
| Others | 1.000 | ||||
| Adenocarcinoma | 2.354 (1.122–4.942) | 0.024 | |||
| Squamous | 5.677 (2.781–11.590) | <0.001 | |||
Hazard ratios and 95% confidence intervals were calculated by a stratified Cox proportional hazards model. P values less than 0.05 are highlighted in italic. LRFS, Local recurrence-free survival; OS, overall survival; CRC, colorectal cancer.