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. 2020 Aug;9(4):1212–1224. doi: 10.21037/tlcr-20-122

Table S8. The top 10 most relevant features (not including clinical factors) for the detection of exon-21 L858R mutation (Model Exon21_A).

Feature AUC MI R2 P
logarithm_glcm_InverseVariance 0.675 0.061 0.097 4.09E-06
original_firstorder_Skewness 0.654 0.06 0.068 1.33E-04
wavelet-LHL_firstorder_Mean 0.643 0.064 0.052 8.75E-04
wavelet-HLL_firstorder_Median 0.666 0.033 0.045 2.02E-03
original_glszm_SizeZoneNonUniformityNormalized 0.614 0.032 0.040 3.34E-03
logarithm_ngtdm_Contrast 0.616 0.086 0.040 3.74E-03
wavelet-HHH_firstorder_Mean 0.601 0.063 0.036 5.71E-03
wavelet-LHL_glcm_ClusterShade 0.597 0.041 0.029 1.38E-02
wavelet-HHH_glszm_GrayLevelVariance 0.591 0.052 0.025 2.10E-02
wavelet-LLL_glszm_ZoneVariance 0.570 0.058 0.020 3.84E-02

AUC, area under the receiver operating characteristic curve; MI, mutual information, represents redundancy; P value is the significance of the minimum redundancy maximum relevance (mRMR).