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. 2020 Sep 9;11:4502. doi: 10.1038/s41467-020-18308-9

Fig. 4. Swelling-triggered transmembrane transport and click reaction.

Fig. 4

a Tensile stress and b variation of tensile stress under different tensile conditions. (1) direct test; (2) test after prestretching at 100% strain for 5 min; (3) test after prestretching at 200% strain for 5 min. c Compressive stress and d variation of compressive stress at 70% strain under different compression conditions. (1) direct test; (2) test after compression at 70% strain for 5 min; (3) test after compression at 70% strain for 10 min. e Relationship between released yet unreacted N3-PEG3-N3 and swelling ratio of the gels with or without Tetra-PEG-DBCO. f Average size of the liposomes embedded in the gels before and after swelling, respectively. Scanning electron microscopy (SEM) images of the lyophilized swelling-strengthening hydrogels (SSHs) (g) before and (h) after fully swelling. Scale bar, 500 nm. Each test was repeated three times independently with similar results. All error bars represent the mean ± SD (n = 3 independent experiments). Significance was assessed using one-way ANOVA with Tukey’s multiple comparisons test, giving P values, ***P < 0.001, ****P < 0.0001.