Fig. 1.

Broad features of RRBS sequencing data from R1 and Tet/Tet ESCs and their corresponding neurons. (A) Number of reads obtained and the proportion of mappable reads in the four cell types. Millions of reads are shown in Y axis against the different cell types on the X-axis. (B) Phred Scores of the RRBS data from the four samples. (C) Distribution of the identified CpG sites with respect to the transcription start sites. (D) Two-component Principal Component Analysis (PCA) of R1 ESCs, Tet/Tet ESCs, R1 neurons and Tet/Tet neurons.