Subject | Anesthesiology and Pain Medicine |
Specific subject area | Reversal of rocuronium neuromuscular blockade with sugammadex or neostigmine. |
Type of data | Table Chart Figure |
How data were acquired | Systematic review and meta-analysis |
Data format | Raw Analyzed |
Parameters for data collection | The primary outcomes recorded were: time to recovery of the train-of-four ratio to > 0.9; total anesthesia time; time from admission to the post-anesthesia recovery unit (PACU) until the patient was ready for discharge from the unit; occurrence of bradycardia; occurrence of post-operative nausea and vomiting (PONV). |
Description of data collection | A search of PubMed, Google Scholar, and Cochrane Library electronic databases identified 111 clinical trials for potential inclusion. We performed screening of citations, data extraction, and quality assessment in duplicate. We performed a meta-analysis of 32 studies that quantitatively compared the efficacy and side effects of sugammadex with either neostigmine or placebo in adult patients requiring general anesthesia. |
Data source location | University of Cincinnati Cincinnati, Ohio United States |
Data accessibility | With the article |
Related research article | Hurford WE, Welge JA, Eckman MH. Sugammadex versus neostigmine for routine reversal of rocuronium block in adult patients: A cost analysis. J. Clin. Anesth. In Press. https://doi.org/10.1016/j.jclinane.2020.110027. |