Table 4.
Compared data of reproductive health-related risk factors | Pregnancy | Puerperium | Oral contraceptive use | p | |||
---|---|---|---|---|---|---|---|
n = 74% | n = 142% | n = 108 | % | ||||
Infections | |||||||
Paracranial (focal) | 2 | 3 | 4 | 3 | 7 | 7 | 0.589 |
Systemic | 1 | 1 | 3 | 2 | 1 | 1 | |
History of VTE | |||||||
Cerebral | 0a | 0 | 1a | 1 | 1a | 1 | |
Deep venous thrombosis | 3a | 4 | 0b | 0 | 0b | 0 | 0.030 |
Other | 0a | 0 | 2a | 1 | 0a | 0 | |
Malignancy | 0 | 0 | 1 | 1 | 0 | 0 | 0.526 |
Family history VTE | 1 | 1 | 0 | 0 | 0 | 0 | 0.228 |
MTHFR mutation | |||||||
Heterozygote, homozygote | 1 | 2 | 5 | 5 | 3 | 5 | 0.385 |
Hyperhomocysteinemia | 1 | 2 | 7 | 7 | 1 | 2 | 0.204 |
Prothrombin mutation | 0 | 0 | 5 | 4 | 4 | 5 | 0.240 |
Protein C/S deficiency | 0 | 0 | 3 | 3 | 4 | 6 | 0.361 |
Factor V Leiden mutation | 3 | 5 | 8 | 7 | 2 | 2 | 0.335 |
Thrombocytosis | 4 | 9 | 3 | 3 | 4 | 6 | 0.716 |
Polycythemia vera | 1 | 2 | 1 | 1 | 0 | 0 | 0.241 |
Anticardiolipin Ab | 0 | 0 | 0 | 0 | 0 | 0 | — |
PAI mutation | 0 | 0 | 1 | 1 | 0 | 0 | 0.517 |
Antithrombin III deficiency | 0 | 0 | 1 | 1 | 1 | 2 | 0.718 |
Hyperfibrinogenemia | 0 | 0 | 0 | 0 | 1 | 1 | 0.568 |
Antiphospholipid Ab | 2 | 3 | 0 | 0 | 0 | 0 | 0.057 |
Activated protein C | 1 | 2 | 3 | 3 | 0 | 0 | 0.362 |
Resistance | 1 | 2 | 1 | 1 | 2 | 2 | 0.821 |
High ANA titers | 0 | 0 | 4 | 4 | 0 | 0 | 0.122 |
First month Rankin | |||||||
0-1 | 49 | 78 | 102 | 78 | 85 | 86 | 0.177 |
2 | 7 | 11 | 18 | 14 | 12 | 12 | |
>3 | 7 | 11 | 11 | 8 | 2 | 2 | |
Third month Rankin | |||||||
0-1 | 45 | 92 | 103 | 89 | 79 | 94 | |
2 | 3 | 6 | 10 | 9 | 4 | 5 | 0.828 |
>3 | 1 | 2 | 3 | 3 | 1 | 1 | |
Sixth month Rankin | |||||||
0-1 | 44 | 96 | 100 | 94 | 71 | 97 | |
2 | 1 | 2 | 4 | 4 | 1 | 1 | 0.937 |
>3 | 1 | 2 | 2 | 2 | 1 | 1 | |
12th month Rankin | |||||||
0-1 | 34 | 97 | 87 | 95 | 64 | 100 | |
2 | 1 | 3 | 3 | 3 | 0 | 0 | 0.409 |
>3 | 0 | 0 | 2 | 2 | 0 | 0 |
ANA: antinuclear antibody; MTHFR: methylenetetrahydrofolate reductase; PAI: plasminogen activator inhibitor; VTE: venous thromboembolism.