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. 2020 Sep 1;2020:8610903. doi: 10.1155/2020/8610903

Table 4.

Etiological factors and outcome of subgroups according to reproductive health-related risks.

Compared data of reproductive health-related risk factors Pregnancy Puerperium Oral contraceptive use p
n = 74% n = 142% n = 108 %
Infections
 Paracranial (focal) 2 3 4 3 7 7 0.589
 Systemic 1 1 3 2 1 1
History of VTE
 Cerebral 0a 0 1a 1 1a 1
 Deep venous thrombosis 3a 4 0b 0 0b 0 0.030
 Other 0a 0 2a 1 0a 0
 Malignancy 0 0 1 1 0 0 0.526
 Family history VTE 1 1 0 0 0 0 0.228
 MTHFR mutation
 Heterozygote, homozygote 1 2 5 5 3 5 0.385
 Hyperhomocysteinemia 1 2 7 7 1 2 0.204
 Prothrombin mutation 0 0 5 4 4 5 0.240
 Protein C/S deficiency 0 0 3 3 4 6 0.361
 Factor V Leiden mutation 3 5 8 7 2 2 0.335
 Thrombocytosis 4 9 3 3 4 6 0.716
 Polycythemia vera 1 2 1 1 0 0 0.241
 Anticardiolipin Ab 0 0 0 0 0 0
 PAI mutation 0 0 1 1 0 0 0.517
 Antithrombin III deficiency 0 0 1 1 1 2 0.718
 Hyperfibrinogenemia 0 0 0 0 1 1 0.568
 Antiphospholipid Ab 2 3 0 0 0 0 0.057
 Activated protein C 1 2 3 3 0 0 0.362
 Resistance 1 2 1 1 2 2 0.821
 High ANA titers 0 0 4 4 0 0 0.122
First month Rankin
 0-1 49 78 102 78 85 86 0.177
 2 7 11 18 14 12 12
 >3 7 11 11 8 2 2
Third month Rankin
 0-1 45 92 103 89 79 94
 2 3 6 10 9 4 5 0.828
 >3 1 2 3 3 1 1
Sixth month Rankin
 0-1 44 96 100 94 71 97
 2 1 2 4 4 1 1 0.937
 >3 1 2 2 2 1 1
12th month Rankin
 0-1 34 97 87 95 64 100
 2 1 3 3 3 0 0 0.409
 >3 0 0 2 2 0 0

ANA: antinuclear antibody; MTHFR: methylenetetrahydrofolate reductase; PAI: plasminogen activator inhibitor; VTE: venous thromboembolism.