Analytical data for (a, b) Vanco-FL-800CW 2, (c, d)
Ampho-800CW 3, and (e, f) Vanco-700DX 4.
(a) Overlay of the PDA spectra of HPLC peaks corresponding to Vanco-FL
(red), IRdye800CW-NHS ester (yellow), and Vanco-FL-800CW (green).
(b) Mass spectrum of the product peak (Figure S9) recorded on a UPLC-MS device. (c) Overlay of PDA spectra
of the HPLC peak corresponding to amphotericin B (blue), IRdye800CW
NHS ester (yellow), and Ampho-800CW (green). (d) Mass spectrum of
the product peak (Figure S10) recorded
on a UPLC-MS device. (e) Overlay of the UV–vis absorption spectra
of vancomycin (blue), IRdye700DX-NHS ester (orange), and Vanco-700DX
(green). The spectra were obtained of the pure samples in 1% DMSO
in water on a UV–vis spectrophotometer. (f) Mass spectrum of
the product peak (Figure S11) recorded
on a UPLC-MS device.