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. 2020 Sep 8;30(9):1338–1345. doi: 10.1089/thy.2019.0711

FIG. 4.

FIG. 4.

Mice immunized with adenovirus containing hTG develop hTG, mTG, and mTPO autoantibodies. (A) Anti-hTG antibodies produced by mice immunized with Ad-LacZ, Ad-TG and induced with classical EAT. (B) Anti-mTG antibodies produced by mice immunized with Ad-LacZ, Ad-TG and induced with classical EAT. (C) Anti-mTPO antibodies produced by mice immunized with Ad-LacZ and Ad-TG. The data are shown as means ± SE. Statistical analysis was performed by using one-way ANOVA followed by Student–Newman–Keuls multiple-comparison test or unpaired t-test. *p < 0.05, ***p < 0.001 (Ad-LacZ, n = 10; Ad-TG, n = 13; EAT, n = 7). mTG, mouse TG; mTPO, mouse thyroperoxidase.