Table 2.
Linear Regression Beta Coefficients of Measures of Insulin Resistance by Alcohol Use Measures Among Men and Women in the New Orleans Alcohol and HIV Study
Log HOMA-IR |
Log Triglycerides Index-IR |
Log McAuley Index-IR |
Log HOMA-β |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
All | Men | Women | All | Men | Women | All | Men | Women | All | Men | Women | |
AUDIT-C | ||||||||||||
β | −0.05 | −0.04 | −0.04 | 3.45 e-4 | −1.20 e-3 | 1.2 e-3 | 0.01 | 0.02 | 6.3 e-3 | −0.06 | −0.06 | −0.03 |
p | <0.01 | 0.04 | 0.24 | 0.75 | 0.34 | 0.56 | <0.01 | 0.02 | 0.54 | <0.01 | <0.01 | 0.39 |
PEth | ||||||||||||
β | −2.5 e-4 | −1.3 e-4 | −1.1 e-3 | −4.8 e-6 | −6.4 e-6 | 9.5 e-6 | 1 e-4 | 7.6 e-5 | 2.3 e-4 | −3.4 e-4 | −2.9e-4 | −7.2 e-4 |
p | 0.03 | 0.26 | 0.01 | 0.4 | 0.43 | 0.73 | <0.01 | 0.06 | 0.09 | <0.01 | 0.02 | 0.07 |
TLFB (g) | ||||||||||||
β | −3.9 e-5 | −3.4 e-5 | −8.6 e-5 | 1.4 e-6 | −7.8 e-7 | 3.5 e-6 | 1.5 e-5 | 2.1 e-5 | 8.1 e-5 | −1.0 e-4 | −1.1 e-4 | −2.0 e-5 |
p | 0.34 | 0.45 | 0.35 | 0.58 | 0.38 | 0.54 | 0.2 | 0.17 | 0.92 | 0.01 | <0.01 | 0.82 |
LDH (g) | ||||||||||||
β | −9.89 e-8 | −4.8 e-8 | −4 e-7 | 1.6 e-8 | 8.60 e-9 | 1.0 e-8 | 1.1 E-8 | 2.6 e-8 | 6.5 e-8 | −2.7 e-7 | −2.8 e-7 | −9.4 e-8 |
p | 0.47 | 0.75 | 0.17 | 0.08 | 0.38 | 0.55 | 0.8 | 0.60 | 0.48 | 0.03 | 0.04 | 0.73 |
All models were adjusted by education, race, BMI, smoking status, viral load, CD4 count, protease inhibitor use, and use of statins or metformin, physical activity, and diabetes diagnosis.
Bold values indicate that the beta coefficients are statistically significant.
AUDIT, Alcohol Use Disorders Identification Test; BMI, body mass index; HOMA-IR, homeostatic model assessment—insulin resistance; HOMA-β, homoeostatic model assessment of beta cell function; PEth, phosphatidylethanol.