Figure 2.

The global allele frequency difference for rs2242480, a single nucleotide polymorphism associated with increased warfarin clearance and lower platelet activation in clopidogrel-treated coronary artery disease patients. As shown, the frequency of the T allele (risk allele) varies widely between populations. Although the frequency is very high in African ancestry populations, followed by South American and Asian populations, it is comparatively very low in European populations.