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. 2020 Sep 10;4(10):bvaa105. doi: 10.1210/jendso/bvaa105

Table 6.

SNPs associated with growth characteristics/IGF status

Clinical/Biological Characteristic Gene Position Corrected P-Value
Sitting height (↓) A2M ENSG_00000175899:g.9110456A > C(Chr12, NCBI38) 0.01621
IGF1 (↓) TP63 ENSG_00000073282:g.189873072G > A(Chr3,NCBI38) 0.04648
HC (↓) DNM3 ENSG_00000005339:g.172407492C > T(Chr3,NCBI38), rs10752946 0.04971

Three haplotype tagging SNPs were significantly associated with sitting height, IGF-I, and head circumference, which were all decreased. A2M encodes alpha-2-macroglobulin, a protease inhibitor and cytokine transporter. TP63 encodes tumour protein p63, a member of a family of transcription factors. DNM3 encodes a member of a family of GTP binding proteins that associate with microtubules and are involved in vesicular transport.